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Compared to controls, children with obesity presented higher concentrations in a variety of metabolites involved in energy homeostasis, branched-chain and aromatic amino acids, markers of oxidative stress, and nucleotide catabolites in both biological matrices, while other metabolic increments were exclusive for plasma (e.g., steroid hormones, bile acids) or erythrocytes (e.g., carnitine derivatives, methionine, N-acetylspermine, sphingolipids)

Recent studies have indicated that GOT1 played critical roles in ferroptosis

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[DOI] [PMC free article] [PubMed] [Google Scholar] 114.Hori I., Harashima H., Yamada Y

Combinations of Treatment Methods As GLP-1 RA and amylin analog-induced weight loss arise from both distinct and overlapping mechanisms, the combination of GLP-1 RA and amylin RA has been shown to produce a synergistic effect [118]